Before administering cefoperazone IV to a patient with hematuria due to UTI, which assessment is appropriate to perform?

Before administering cefoperazone IV to a patient with hematuria due to UTI, which assessment is appropriate to perform?

• A. Monitor the PT/IN before administering the dose.
• B. Check the patient for allergies.
• C. Monitor the blood pressure before and after the dose.
• D. Assess the white blood cell count.

Answer: (C)

Monitoring blood pressure before and after giving cefoperazone IV is essential because certain IV antibiotics can cause infusion-related reactions that affect hemodynamics. A drop in blood pressure during or after the infusion can signal a hypersensitivity or infusion reaction, and detecting it early allows immediate actions—slowing or stopping the infusion, adjusting the rate, and initiating appropriate support. While checking for allergies is important in general, the most immediate safety assessment for this IV antibiotic is to watch the blood pressure to prevent potential adverse hemodynamic effects.

Monitoring blood pressure before and after giving cefoperazone IV is essential because certain IV antibiotics can cause infusion-related reactions that affect hemodynamics. A drop in blood pressure during or after the infusion can signal a hypersensitivity or infusion reaction, and detecting it early allows immediate actions—slowing or stopping the infusion, adjusting the rate, and initiating appropriate support. While checking for allergies is important in general, the most immediate safety assessment for this IV antibiotic is to watch the blood pressure to prevent potential adverse hemodynamic effects.